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Suppression of Spry4 enhances cancer stem cell properties of human MDA-MB-231 breast carcinoma cells

BACKGROUND: Cancer stem cells contribute to tumor initiation, heterogeneity, and recurrence, and are critical targets in cancer therapy. Sprouty4 (Spry4) is a potent inhibitor of signal transduction pathways elicited by receptor tyrosine kinases, and has roles in regulating cell proliferation, migra...

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Detalles Bibliográficos
Autores principales:	Jing, Hongyu, Liaw, Lucy, Friesel, Robert, Vary, Calvin, Hua, Shucheng, Yang, Xuehui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787021/ https://www.ncbi.nlm.nih.gov/pubmed/26973433 http://dx.doi.org/10.1186/s12935-016-0292-7

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