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Genomes to natural products PRediction Informatics for Secondary Metabolomes (PRISM)

Microbial natural products are an invaluable source of evolved bioactive small molecules and pharmaceutical agents. Next-generation and metagenomic sequencing indicates untapped genomic potential, yet high rediscovery rates of known metabolites increasingly frustrate conventional natural product scr...

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Detalles Bibliográficos
Autores principales: Skinnider, Michael A., Dejong, Chris A., Rees, Philip N., Johnston, Chad W., Li, Haoxin, Webster, Andrew L. H., Wyatt, Morgan A., Magarvey, Nathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787774/
https://www.ncbi.nlm.nih.gov/pubmed/26442528
http://dx.doi.org/10.1093/nar/gkv1012