GC skew is a conserved property of unmethylated CpG island promoters across vertebrates

GC skew is a measure of the strand asymmetry in the distribution of guanines and cytosines. GC skew favors R-loops, a type of three stranded nucleic acid structures that form upon annealing of an RNA strand to one strand of DNA, creating a persistent RNA:DNA hybrid. Previous studies show that GC ske...

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Detalles Bibliográficos
Autores principales: Hartono, Stella R., Korf, Ian F., Chédin, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787789/
https://www.ncbi.nlm.nih.gov/pubmed/26253743
http://dx.doi.org/10.1093/nar/gkv811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787789/
https://www.ncbi.nlm.nih.gov/pubmed/26253743
http://dx.doi.org/10.1093/nar/gkv811

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