Post-transcriptional gene silencing triggered by sense transgenes involves uncapped antisense RNA and differs from silencing intentionally triggered by antisense transgenes

Although post-transcriptional gene silencing (PTGS) has been studied for more than a decade, there is still a gap in our understanding of how de novo silencing is initiated against genetic elements that are not supposed to produce double-stranded (ds)RNA. Given the pervasive transcription occurring...

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Detalles Bibliográficos
Autores principales: Parent, Jean-Sébastien, Jauvion, Vincent, Bouché, Nicolas, Béclin, Christophe, Hachet, Mélanie, Zytnicki, Matthias, Vaucheret, Hervé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787800/
https://www.ncbi.nlm.nih.gov/pubmed/26209135
http://dx.doi.org/10.1093/nar/gkv753

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