Cargando…
Structural basis for selective targeting of leishmanial ribosomes: aminoglycoside derivatives as promising therapeutics
Leishmaniasis comprises an array of diseases caused by pathogenic species of Leishmania, resulting in a spectrum of mild to life-threatening pathologies. Currently available therapies for leishmaniasis include a limited selection of drugs. This coupled with the rather fast emergence of parasite resi...
Autores principales: | Shalev, Moran, Rozenberg, Haim, Smolkin, Boris, Nasereddin, Abedelmajeed, Kopelyanskiy, Dmitry, Belakhov, Valery, Schrepfer, Thomas, Schacht, Jochen, Jaffe, Charles L., Adir, Noam, Baasov, Timor |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787808/ https://www.ncbi.nlm.nih.gov/pubmed/26264664 http://dx.doi.org/10.1093/nar/gkv821 |
Ejemplares similares
-
Balancing
Nonsense Mutation Readthrough and Toxicity
of Designer Aminoglycosides for Treatment of Genetic Diseases
por: Guchhait, Sandip, et al.
Publicado: (2023) -
Readthrough of nonsense mutations in Rett syndrome: evaluation of novel aminoglycosides and generation of a new mouse model
por: Brendel, Cornelia, et al.
Publicado: (2010) -
Erratum to: Readthrough of nonsense mutations in Rett syndrome: evaluation of novel aminoglycosides and generation of a new mouse model
por: Brendel, Cornelia, et al.
Publicado: (2013) -
Atomic resolution snapshot of Leishmania ribosome inhibition by the aminoglycoside paromomycin
por: Shalev-Benami, Moran, et al.
Publicado: (2017) -
Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus
por: Matzov, Donna, et al.
Publicado: (2017)