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Efficient Strategies for Calculating Blockwise Likelihoods Under the Coalescent

The inference of demographic history from genome data is hindered by a lack of efficient computational approaches. In particular, it has proved difficult to exploit the information contained in the distribution of genealogies across the genome. We have previously shown that the generating function (...

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Detalles Bibliográficos
Autores principales: Lohse, Konrad, Chmelik, Martin, Martin, Simon H., Barton, Nicholas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788249/
https://www.ncbi.nlm.nih.gov/pubmed/26715666
http://dx.doi.org/10.1534/genetics.115.183814