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Screening of the Open Source Malaria Box Reveals an Early Lead Compound for the Treatment of Alveolar Echinococcosis
The metacestode (larval) stage of the tapeworm Echinococcus multilocularis causes alveolar echinococcosis (AE), a very severe and in many cases incurable disease. To date, benzimidazoles such as albendazole and mebendazole are the only approved chemotherapeutical treatment options. Benzimidazoles in...
Autores principales: | Stadelmann, Britta, Rufener, Reto, Aeschbacher, Denise, Spiliotis, Markus, Gottstein, Bruno, Hemphill, Andrew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788259/ https://www.ncbi.nlm.nih.gov/pubmed/26967740 http://dx.doi.org/10.1371/journal.pntd.0004535 |
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