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High-Resolution Mapping of Homologous Recombination Events in rad3 Hyper-Recombination Mutants in Yeast

The Saccharomyces cerevisae RAD3 gene is the homolog of human XPD, an essential gene encoding a DNA helicase of the TFIIH complex involved in both nucleotide excision repair (NER) and transcription. Some mutant alleles of RAD3 (rad3-101 and rad3-102) have partial defects in DNA repair and a strong h...

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Detalles Bibliográficos
Autores principales: Andersen, Sabrina L., Zhang, Aimee, Dominska, Margaret, Moriel-Carretero, María, Herrera-Moyano, Emilia, Aguilera, Andrés, Petes, Thomas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788294/
https://www.ncbi.nlm.nih.gov/pubmed/26968037
http://dx.doi.org/10.1371/journal.pgen.1005938