Asparaginase Potentiates Glucocorticoid-Induced Osteonecrosis in a Mouse Model

Osteonecrosis is a common dose-limiting toxicity of glucocorticoids. Data from clinical trials suggest that other medications can increase the risk of glucocorticoid-induced osteonecrosis. Here we utilized a mouse model to study the effect of asparaginase treatment on dexamethasone-induced osteonecr...

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Detalles Bibliográficos
Autores principales: Liu, Chengcheng, Janke, Laura J., Kawedia, Jitesh D., Ramsey, Laura B., Cai, Xiangjun, Mattano, Leonard A., Boyd, Kelli L., Funk, Amy J., Relling, Mary V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788417/
https://www.ncbi.nlm.nih.gov/pubmed/26967741
http://dx.doi.org/10.1371/journal.pone.0151433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788417/
https://www.ncbi.nlm.nih.gov/pubmed/26967741
http://dx.doi.org/10.1371/journal.pone.0151433

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