Cargando…

Asparaginase Potentiates Glucocorticoid-Induced Osteonecrosis in a Mouse Model

Osteonecrosis is a common dose-limiting toxicity of glucocorticoids. Data from clinical trials suggest that other medications can increase the risk of glucocorticoid-induced osteonecrosis. Here we utilized a mouse model to study the effect of asparaginase treatment on dexamethasone-induced osteonecr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Chengcheng, Janke, Laura J., Kawedia, Jitesh D., Ramsey, Laura B., Cai, Xiangjun, Mattano, Leonard A., Boyd, Kelli L., Funk, Amy J., Relling, Mary V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788417/ https://www.ncbi.nlm.nih.gov/pubmed/26967741 http://dx.doi.org/10.1371/journal.pone.0151433

Ejemplares similares

Asparaginase combined with discontinuous dexamethasone improves antileukemic efficacy without increasing osteonecrosis in preclinical models
por: Karol, Seth E., et al.
Publicado: (2019)

Fenofibrate reduces osteonecrosis without affecting antileukemic efficacy in dexamethasone-treated mice
por: Finch, Emily R., et al.
Publicado: (2020)

Hypersensitivity reactions to asparaginase in mice are mediated by anti-asparaginase IgE and IgG and the immunoglobulin receptors FcεRI and FcγRIII
por: Rathod, Sanjay, et al.
Publicado: (2019)

Prevalence of glucocorticoid induced osteonecrosis in the mouse is not affected by treatments that maintain bone vascularity
por: Lane, Nancy E., et al.
Publicado: (2018)

Antileukemic Efficacy of Continuous vs Discontinuous Dexamethasone in Murine Models of Acute Lymphoblastic Leukemia
por: Ramsey, Laura B., et al.
Publicado: (2015)

Role of coagulopathy in glucocorticoid-induced osteonecrosis of the femoral head
por: Zhang, Qiankun, et al.
Publicado: (2017)

Glucocorticoid‐induced osteonecrosis in systemic lupus erythematosus patients
por: Kaneko, Kaichi, et al.
Publicado: (2021)

Extensive Osteonecrosis After Glucocorticoids: Clinical Response to Bisphosphonate
por: Subbu, Karthik, et al.
Publicado: (2022)

A rat model of early stage osteonecrosis induced by glucocorticoids
por: Kerachian, Mohammad Amin, et al.
Publicado: (2011)

Oral glucocorticoid use and osteonecrosis in children and adults with chronic inflammatory diseases: a population-based cohort study
por: Horton, Daniel B, et al.
Publicado: (2017)

Glucocorticoids in osteonecrosis of the femoral head: A new understanding of the mechanisms of action
por: Kerachian, Mohammad Amin, et al.
Publicado: (2009)

Assessment of l-Asparaginase Pharmacodynamics in Mouse Models of Cancer
por: Horvath, Thomas D., et al.
Publicado: (2019)

Risk factors for multi-joint disease in patients with glucocorticoid-induced osteonecrosis
por: Krez, A., et al.
Publicado: (2021)

The Pathophysiological Sequence of Glucocorticoid-Induced Osteonecrosis of the Femoral Head in Male Mice
por: Weinstein, Robert S., et al.
Publicado: (2017)

The Protective Effect of Luteolin in Glucocorticoid-Induced Osteonecrosis of the Femoral Head
por: Yan, Zijian, et al.
Publicado: (2020)

Strain-specific differences in the development of bone loss and incidence of osteonecrosis following glucocorticoid treatment in two different mouse strains
por: Shidara, Kie, et al.
Publicado: (2018)

Effects of angiotensin II combined with asparaginase and dexamethasone on the femoral head in mice: A model of steroid-induced femoral head osteonecrosis
por: Liu, Jiahe, et al.
Publicado: (2022)

Valproic acid prevents glucocorticoid-induced osteonecrosis of the femoral head of rats
por: Zhou, Ding, et al.
Publicado: (2018)

Glucocorticoids induce osteonecrosis of the femoral head through the Hippo signaling pathway
por: Li, Yugang, et al.
Publicado: (2021)

Osteonecrosis in Primary Antiphospholipid Syndrome is Associated with Previous Glucocorticoid Use and Thrombocytopenia
por: Freire de Carvalho, Jozélio, et al.
Publicado: (2021)

SIRT6 Prevents Glucocorticoid-Induced Osteonecrosis of the Femoral Head in Rats
por: Fang, Lun, et al.
Publicado: (2022)

Glucocorticoid suppression of osteocyte perilacunar remodeling is associated with subchondral bone degeneration in osteonecrosis
por: Fowler, Tristan W., et al.
Publicado: (2017)

The efficacy of statins in preventing glucocorticoid-related osteonecrosis in animal models: A meta-analysis
por: Yang, Z., et al.
Publicado: (2016)

Vitamin K(2) Prevents Glucocorticoid-induced Osteonecrosis of the Femoral Head in Rats
por: Zhang, Yue-Lei, et al.
Publicado: (2016)

Relation between the development of osteoporosis and osteonecrosis following glucocorticoid in a rabbit model
por: Lin, Tao, et al.
Publicado: (2016)

Screening and identification of potential key biomarkers for glucocorticoid-induced osteonecrosis of the femoral head
por: Chen, Dan, et al.
Publicado: (2023)

Mechanistic studies of PEG-asparaginase-induced liver injury and hepatic steatosis in mice
por: Kumar, Gundala Venkata Naveen, et al.
Publicado: (2021)

SUPPRESSION OF MURINE LEUKEMIAS BY L-ASPARAGINASE : INCIDENCE OF SENSITIVITY AMONG LEUKEMIAS OF VARIOUS TYPES: COMPARATIVE INHIBITORY ACTIVITIES OF GUINEA PIG SERUML-ASPARAGINASE AND ESCHERICHIA COLI L-ASPARAGINASE
por: Boyse, Edward A., et al.
Publicado: (1967)

Allergic Reactions to E. coli Asparaginase are Associated with Decreased Asparaginase Activity in an Indonesian Pediatric Population with ALL
por: Sari, Nur Melani, et al.
Publicado: (2023)

Less sclerotic microarchitecture pattern with increased bone resorption in glucocorticoid-associated osteonecrosis of femoral head as compared to alcohol-associated osteonecrosis of femoral head
por: Chen, Yiwei, et al.
Publicado: (2023)

Icariin promotes angiogenesis in glucocorticoid‐induced osteonecrosis of femoral heads: In vitro and in vivo studies
por: Yu, Huachen, et al.
Publicado: (2019)

General recommendation for assessment and management on the risk of glucocorticoid-induced osteonecrosis in patients with COVID-19
por: Li, Wenlong, et al.
Publicado: (2021)

Glucocorticoid-induced loss of beneficial gut bacterial extracellular vesicles is associated with the pathogenesis of osteonecrosis
por: Chen, Chun-Yuan, et al.
Publicado: (2022)

Identification and Validation of Potential Ferroptosis-Related Genes in Glucocorticoid-Induced Osteonecrosis of the Femoral Head
por: Chen, Ning, et al.
Publicado: (2023)

Amino acid stress response genes promote L-asparaginase resistance in pediatric acute lymphoblastic leukemia
por: Ferguson, Daniel C., et al.
Publicado: (2022)

Update on Medication Related Osteonecrosis of the Jaws
por: Boyd, Barry C.
Publicado: (2023)

Hypoxia and Hypoxia Mimetics Decrease Aquaporin 5 (AQP5) Expression through Both Hypoxia Inducible Factor-1α and Proteasome-Mediated Pathways
por: Kawedia, Jitesh D., et al.
Publicado: (2013)

Administration of erythropoietin exerts protective effects against glucocorticoid-induced osteonecrosis of the femoral head in rats
por: CHEN, SEN, et al.
Publicado: (2014)

Prevention of glucocorticoid-associated osteonecrosis by intravenous administration of mesenchymal stem cells in a rabbit model
por: Ueda, Shusuke, et al.
Publicado: (2017)

Taurine Inhibits Glucocorticoid-Induced Bone Mitochondrial Injury, Preventing Osteonecrosis in Rabbits and Cultured Osteocytes
por: Hirata, Hiroaki, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_j3fp8bc6u007dp19b1scetsqfg