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Reorganization of chromosome architecture in replicative cellular senescence

Replicative cellular senescence is a fundamental biological process characterized by an irreversible arrest of proliferation. Senescent cells accumulate a variety of epigenetic changes, but the three-dimensional (3D) organization of their chromatin is not known. We applied a combination of whole-gen...

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Detalles Bibliográficos
Autores principales:	Criscione, Steven W., De Cecco, Marco, Siranosian, Benjamin, Zhang, Yue, Kreiling, Jill A., Sedivy, John M., Neretti, Nicola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2016
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788486/ https://www.ncbi.nlm.nih.gov/pubmed/26989773 http://dx.doi.org/10.1126/sciadv.1500882

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