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High fat diet impairs the function of glucagon-like peptide-1 producing L-cells

Glucagon-like peptide-1 (GLP-1) acts as a satiety signal and enhances insulin release. This study examined how GLP-1 production from intestinal L-cells is modified by dietary changes. METHODS: Transgenic mouse models were utilized in which L-cells could be purified by cell specific expression of a y...

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Detalles Bibliográficos
Autores principales:	Richards, Paul, Pais, Ramona, Habib, Abdella M., Brighton, Cheryl A., Yeo, Giles S.H., Reimann, Frank, Gribble, Fiona M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science Inc 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788507/ https://www.ncbi.nlm.nih.gov/pubmed/26145551 http://dx.doi.org/10.1016/j.peptides.2015.06.006

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