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Differential surface activation of the A1 domain of von Willebrand factor

The clotting protein von Willebrand factor (VWF) binds to platelet receptor glycoprotein Ibα (GPIbα) when VWF is activated by chemicals, high shear stress, or immobilization onto surfaces. Activation of VWF by surface immobilization is an important problem in the failure of cardiovascular implants,...

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Detalles Bibliográficos
Autores principales:	Tronic, Elaine H., Yakovenko, Olga, Weidner, Tobias, Baio, Joe E., Penkala, Rebecca, Castner, David G., Thomas, Wendy E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Vacuum Society 2016
Materias:	In Focus: Blood-Biomaterial Interactions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788635/ https://www.ncbi.nlm.nih.gov/pubmed/26968213 http://dx.doi.org/10.1116/1.4943618

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