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A new method to quantify tau pathologies with (11)C-PBB3 PET using reference tissue voxels extracted from brain cortical gray matter

BACKGROUND: Quantitative in vivo imaging of tau pathologies potentially improves diagnostic accuracy of neurodegenerative tauopathies and would facilitate evaluation of disease-modifying drugs targeting tau lesions in these diseases. Tau pathology can be quantified by reference tissue models without...

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Detalles Bibliográficos
Autores principales: Kimura, Yasuyuki, Endo, Hironobu, Ichise, Masanori, Shimada, Hitoshi, Seki, Chie, Ikoma, Yoko, Shinotoh, Hitoshi, Yamada, Makiko, Higuchi, Makoto, Zhang, Ming-Rong, Suhara, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788664/
https://www.ncbi.nlm.nih.gov/pubmed/26969002
http://dx.doi.org/10.1186/s13550-016-0182-y