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Oncometabolic Nuclear Reprogramming of Cancer Stemness

By impairing histone demethylation and locking cells into a reprogramming-prone state, oncometabolites can partially mimic the process of induced pluripotent stem cell generation. Using a systems biology approach, combining mathematical modeling, computation, and proof-of-concept studies with live c...

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Detalles Bibliográficos
Autores principales:	Menendez, Javier A., Corominas-Faja, Bruna, Cuyàs, Elisabet, García, María G., Fernández-Arroyo, Salvador, Fernández, Agustín F., Joven, Jorge, Fraga, Mario F., Alarcón, Tomás
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788754/ https://www.ncbi.nlm.nih.gov/pubmed/26876667 http://dx.doi.org/10.1016/j.stemcr.2015.12.012

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