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GATA Factor-G-Protein-Coupled Receptor Circuit Suppresses Hematopoiesis

Hematopoietic stem cells (HSCs) originate from hemogenic endothelium within the aorta-gonad-mesonephros (AGM) region of the mammalian embryo. The relationship between genetic circuits controlling stem cell genesis and multi-potency is not understood. A Gata2 cis element (+9.5) enhances Gata2 express...

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Detalles Bibliográficos
Autores principales:	Gao, Xin, Wu, Tongyu, Johnson, Kirby D., Lahvic, Jamie L., Ranheim, Erik A., Zon, Leonard I., Bresnick, Emery H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788764/ https://www.ncbi.nlm.nih.gov/pubmed/26905203 http://dx.doi.org/10.1016/j.stemcr.2016.01.008

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