Cardiomyocytes Derived from MHC-Homozygous Induced Pluripotent Stem Cells Exhibit Reduced Allogeneic Immunogenicity in MHC-Matched Non-human Primates

Induced pluripotent stem cells (iPSCs) can serve as a source of cardiomyocytes (CMs) to treat end-stage heart failure; however, transplantation of genetically dissimilar iPSCs even within species (allogeneic) can induce immune rejection. We hypothesized that this might be limited by matching the maj...

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Detalles Bibliográficos
Autores principales: Kawamura, Takuji, Miyagawa, Shigeru, Fukushima, Satsuki, Maeda, Akira, Kashiyama, Noriyuki, Kawamura, Ai, Miki, Kenji, Okita, Keisuke, Yoshida, Yoshinori, Shiina, Takashi, Ogasawara, Kazumasa, Miyagawa, Shuji, Toda, Koichi, Okuyama, Hiroomi, Sawa, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788782/
https://www.ncbi.nlm.nih.gov/pubmed/26905198
http://dx.doi.org/10.1016/j.stemcr.2016.01.012

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