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Photoreceptor proliferation and dysregulation of cell cycle genes in early onset inherited retinal degenerations
BACKGROUND: Mitotic terminally differentiated photoreceptors (PRs) are observed in early retinal degeneration (erd), an inherited canine retinal disease driven by mutations in the NDR kinase STK38L (NDR2). RESULTS: We demonstrate that a similar proliferative response, but of lower magnitude, occurs...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788844/ https://www.ncbi.nlm.nih.gov/pubmed/26969498 http://dx.doi.org/10.1186/s12864-016-2477-9 |