Treatment with TO901317, a synthetic liver X receptor agonist, reduces brain damage and attenuates neuroinflammation in experimental intracerebral hemorrhage

BACKGROUND: Intracerebral hemorrhage (ICH) induces a series of inflammatory processes that contribute to neuronal damage and neurological deterioration. Liver X receptors (LXRs) are nuclear receptors that negatively regulate transcriptional processes involved in inflammatory responses, but their rol...

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Detalles Bibliográficos
Autores principales: Wu, Chun-Hu, Chen, Chien-Cheng, Lai, Chai-You, Hung, Tai-Ho, Lin, Chao-Chang, Chao, Min, Chen, Szu-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788882/
https://www.ncbi.nlm.nih.gov/pubmed/26968836
http://dx.doi.org/10.1186/s12974-016-0524-8

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