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SNPs in FNDC5 (irisin) are associated with obesity and modulation of glucose and lipid metabolism in Saudi subjects

BACKGROUND: Irisin is a recently identified myokine that plays an important role in preventing obesity and insulin resistance. We investigated whether the common FNDC5 (irisin precursor) gene variants influence susceptibility to obesity and type 2 diabetes (T2D) and verified the impact of FNDC5 gene...

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Detalles Bibliográficos
Autores principales: Al-Daghri, Nasser M., Mohammed, Abdul Khader, Al-Attas, Omar S., Amer, Osama E., Clerici, Mario, Alenad, Amal, Alokail, Majed S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788945/
https://www.ncbi.nlm.nih.gov/pubmed/26968837
http://dx.doi.org/10.1186/s12944-016-0224-5