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Intracerebroventricular Streptozotocin Injections as a Model of Alzheimer’s Disease: in Search of a Relevant Mechanism
Streptozotocin (STZ), a glucosamine-nitrosourea compound derived from soil bacteria and originally developed as an anticancer agent, in 1963 has been found to induce diabetes in experimental animals. Since then, systemic application of STZ became the most frequently studied experimental model of ins...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer US
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789228/ https://www.ncbi.nlm.nih.gov/pubmed/25744568 http://dx.doi.org/10.1007/s12035-015-9132-3 |