Lymphatic endothelial cells efferent to inflamed joints produce iNOS and inhibit lymphatic vessel contraction and drainage in TNF-induced arthritis in mice

BACKGROUND: In this study, we sought to determine the cellular source of inducible nitric oxide synthase (iNOS) induced in lymphatic endothelial cells (LECs) in response to tumor necrosis factor (TNF), the effects of iNOS on lymphatic smooth muscle cell (LSMC) function and on the development of arth...

Descripción completa

Detalles Bibliográficos
Autores principales: Liang, Qianqian, Ju, Yawen, Chen, Yan, Wang, Wensheng, Li, Jinlong, Zhang, Li, Xu, Hao, Wood, Ronald W., Schwarz, Edward. M., Boyce, Brendan F., Wang, Yongjun, Xing, Lianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789262/
https://www.ncbi.nlm.nih.gov/pubmed/26970913
http://dx.doi.org/10.1186/s13075-016-0963-8

Ejemplares similares

Ejemplares similares