Detection and monitoring of human bocavirus 1 infection by a new rapid antigen test

Clinically relevant diagnosis of human bocavirus 1 (HBoV1) is challenging, as the virus is frequently detected in asymptomatic patients, and cofindings with other respiratory viruses are common. The clinical value of current diagnostic methods, such as PCR, is therefore low, and alternative diagnost...

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Detalles Bibliográficos
Autores principales: Bruning, A.H.L., Susi, P., Toivola, H., Christensen, A., Söderlund-Venermo, M., Hedman, K., Aatola, H., Zvirbliene, A., Koskinen, J.O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
New Technologies for Infectious and Tropical Diseases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789334/
https://www.ncbi.nlm.nih.gov/pubmed/27014463
http://dx.doi.org/10.1016/j.nmni.2016.01.015
Descripción
Sumario:Clinically relevant diagnosis of human bocavirus 1 (HBoV1) is challenging, as the virus is frequently detected in asymptomatic patients, and cofindings with other respiratory viruses are common. The clinical value of current diagnostic methods, such as PCR, is therefore low, and alternative diagnostic strategies are needed. We describe for the first time the use of an antigen detection assay for the rapid identification of HBoV1 in a paediatric patient with respiratory tract infection symptoms. We estimate the duration of active HBoV1 infection to be 6 days.

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