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High Yielding Microbubble Production Method
Microfluidic approaches to microbubble production are generally disadvantaged by low yield and high susceptibility to (micro)channel blockages. This paper presents an alternative method of producing microbubbles of 2.6 μm mean diameter at concentrations in excess of 30 × 10(6) mL(−1). In this method...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789381/ https://www.ncbi.nlm.nih.gov/pubmed/27034935 http://dx.doi.org/10.1155/2016/3572827 |
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author | Fiabane, Joe Prentice, Paul Pancholi, Ketan |
author_facet | Fiabane, Joe Prentice, Paul Pancholi, Ketan |
author_sort | Fiabane, Joe |
collection | PubMed |
description | Microfluidic approaches to microbubble production are generally disadvantaged by low yield and high susceptibility to (micro)channel blockages. This paper presents an alternative method of producing microbubbles of 2.6 μm mean diameter at concentrations in excess of 30 × 10(6) mL(−1). In this method, the nitrogen gas flowing inside the liquid jet is disintegrated into spray of microbubble when air surrounding this coflowing nitrogen gas-liquid jet passes through a 100 μm orifice at high velocity. Resulting microbubble foam has the polydispersity index of 16%. Moreover, a ratio of mean microbubble diameter to channel width ratio was found to be less than 0.025, which substantially alleviates the occurrence of blockages during production. |
format | Online Article Text |
id | pubmed-4789381 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-47893812016-03-31 High Yielding Microbubble Production Method Fiabane, Joe Prentice, Paul Pancholi, Ketan Biomed Res Int Research Article Microfluidic approaches to microbubble production are generally disadvantaged by low yield and high susceptibility to (micro)channel blockages. This paper presents an alternative method of producing microbubbles of 2.6 μm mean diameter at concentrations in excess of 30 × 10(6) mL(−1). In this method, the nitrogen gas flowing inside the liquid jet is disintegrated into spray of microbubble when air surrounding this coflowing nitrogen gas-liquid jet passes through a 100 μm orifice at high velocity. Resulting microbubble foam has the polydispersity index of 16%. Moreover, a ratio of mean microbubble diameter to channel width ratio was found to be less than 0.025, which substantially alleviates the occurrence of blockages during production. Hindawi Publishing Corporation 2016 2016-02-29 /pmc/articles/PMC4789381/ /pubmed/27034935 http://dx.doi.org/10.1155/2016/3572827 Text en Copyright © 2016 Joe Fiabane et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Fiabane, Joe Prentice, Paul Pancholi, Ketan High Yielding Microbubble Production Method |
title | High Yielding Microbubble Production Method |
title_full | High Yielding Microbubble Production Method |
title_fullStr | High Yielding Microbubble Production Method |
title_full_unstemmed | High Yielding Microbubble Production Method |
title_short | High Yielding Microbubble Production Method |
title_sort | high yielding microbubble production method |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789381/ https://www.ncbi.nlm.nih.gov/pubmed/27034935 http://dx.doi.org/10.1155/2016/3572827 |
work_keys_str_mv | AT fiabanejoe highyieldingmicrobubbleproductionmethod AT prenticepaul highyieldingmicrobubbleproductionmethod AT pancholiketan highyieldingmicrobubbleproductionmethod |