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Evaluation of a High-Throughput Peptide Reactivity Format Assay for Assessment of the Skin Sensitization Potential of Chemicals

The direct peptide reactivity assay (DPRA) is a validated method for in vitro assessment of the skin sensitization potential of chemicals. In the present work, we describe a peptide reactivity assay using 96-well plate format and systematically identified the optimal assay conditions for accurate an...

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Detalles Bibliográficos
Autores principales: Wong, Chin Lin, Lam, Ai-Leen, Smith, Maree T., Ghassabian, Sussan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789461/
https://www.ncbi.nlm.nih.gov/pubmed/27014067
http://dx.doi.org/10.3389/fphar.2016.00053