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A global profile of replicative polymerase usage
Three eukaryotic DNA polymerases are essential for genome replication. Polα-primase initiates each synthesis event and is rapidly replaced by processive DNA polymerases: Polε replicates the leading strand while Polδ performs lagging strand synthesis. However, it is not known whether this division of...
Autores principales: | Daigaku, Yasukazu, Keszthelyi, Andrea, Müller, Carolin A., Miyabe, Izumi, Brooks, Tony, Retkute, Renata, Hubank, Mike, Nieduszynski, Conrad A., Carr, Antony M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789492/ https://www.ncbi.nlm.nih.gov/pubmed/25664722 http://dx.doi.org/10.1038/nsmb.2962 |
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