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Atomic visualization of a flipped-back conformation of bisected glycans bound to specific lectins
Glycans normally exist as a dynamic equilibrium of several conformations. A fundamental question concerns how such molecules bind lectins despite disadvantageous entropic loss upon binding. Bisected glycan, a glycan possessing bisecting N-acetylglucosamine (GlcNAc), is potentially a good model for i...
Autores principales: | Nagae, Masamichi, Kanagawa, Mayumi, Morita-Matsumoto, Kana, Hanashima, Shinya, Kizuka, Yasuhiko, Taniguchi, Naoyuki, Yamaguchi, Yoshiki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789653/ https://www.ncbi.nlm.nih.gov/pubmed/26971576 http://dx.doi.org/10.1038/srep22973 |
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