Cargando…

hTERT promotes cell adhesion and migration independent of telomerase activity

hTERT, a catalytic component of human telomerase, is undetectable in normal somatic cells but up-regulated in cancer and stem cells where telomere length is maintained by telomerase. Accumulated evidence indicates that hTERT may have noncanonical functions beyond telomerase by regulating the express...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Haiying, Liu, Qianqian, Ge, Yuanlong, Zhao, Qi, Zheng, Xiaohui, Zhao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789728/
https://www.ncbi.nlm.nih.gov/pubmed/26971878
http://dx.doi.org/10.1038/srep22886