Identification of novel RNA secondary structures within the hepatitis C virus genome reveals a cooperative involvement in genome packaging

The specific packaging of the hepatitis C virus (HCV) genome is hypothesised to be driven by Core-RNA interactions. To identify the regions of the viral genome involved in this process, we used SELEX (systematic evolution of ligands by exponential enrichment) to identify RNA aptamers which bind spec...

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Detalles Bibliográficos
Autores principales: Stewart, H., Bingham, R.J., White, S. J., Dykeman, E. C., Zothner, C., Tuplin, A. K., Stockley, P. G., Twarock, R., Harris, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789732/
https://www.ncbi.nlm.nih.gov/pubmed/26972799
http://dx.doi.org/10.1038/srep22952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789732/
https://www.ncbi.nlm.nih.gov/pubmed/26972799
http://dx.doi.org/10.1038/srep22952

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