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Holliday Junction Thermodynamics and Structure: Coarse-Grained Simulations and Experiments

Holliday junctions play a central role in genetic recombination, DNA repair and other cellular processes. We combine simulations and experiments to evaluate the ability of the 3SPN.2 model, a coarse-grained representation designed to mimic B-DNA, to predict the properties of DNA Holliday junctions....

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Detalles Bibliográficos
Autores principales:	Wang, Wujie, Nocka, Laura M., Wiemann, Brianne Z., Hinckley, Daniel M., Mukerji, Ishita, Starr, Francis W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789735/ https://www.ncbi.nlm.nih.gov/pubmed/26971574 http://dx.doi.org/10.1038/srep22863

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