Palmoplantar keratoderma in Slurp2-deficient mice

SLURP1, a member of the Ly6 protein family, is secreted by suprabasal keratinocytes. Mutations in SLURP1 cause a palmoplantar keratoderma (PPK) known as mal de Meleda. Another secreted Ly6 protein, SLURP2, is encoded by a gene located ~20 kb downstream from SLURP1. SLURP2 is produced by suprabasal k...

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Detalles Bibliográficos
Autores principales: Allan, Christopher M., Procaccia, Shiri, Tran, Deanna, Tu, Yiping, Barnes, Richard H., Larsson, Mikael, Allan, Bernard B., Young, Lorraine C., Hong, Cynthia, Tontonoz, Peter, Fong, Loren G., Young, Stephen G., Beigneux, Anne P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789766/
https://www.ncbi.nlm.nih.gov/pubmed/26967477
http://dx.doi.org/10.1016/j.jid.2015.11.003

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