Spotlight on botulinum toxin and its potential in the treatment of stroke-related spasticity

Poststroke spasticity affects up to one-half of stroke patients and has debilitating effects, contributing to diminished activities of daily living, quality of life, pain, and functional impairments. Botulinum toxin (BoNT) is proven to be safe and effective in the treatment of focal poststroke spast...

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Detalles Bibliográficos
Autores principales: Kaku, Michelle, Simpson, David M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789850/
https://www.ncbi.nlm.nih.gov/pubmed/27022247
http://dx.doi.org/10.2147/DDDT.S80804
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author Kaku, Michelle
Simpson, David M
author_facet Kaku, Michelle
Simpson, David M
author_sort Kaku, Michelle
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description Poststroke spasticity affects up to one-half of stroke patients and has debilitating effects, contributing to diminished activities of daily living, quality of life, pain, and functional impairments. Botulinum toxin (BoNT) is proven to be safe and effective in the treatment of focal poststroke spasticity. The aim of this review is to highlight BoNT and its potential in the treatment of upper and lower limb poststroke spasticity. We review evidence for the efficacy of BoNT type A and B formulations and address considerations of optimal injection technique, patient and caregiver satisfaction, and potential adverse effects of BoNT.
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spelling pubmed-47898502016-03-28 Spotlight on botulinum toxin and its potential in the treatment of stroke-related spasticity Kaku, Michelle Simpson, David M Drug Des Devel Ther Review Poststroke spasticity affects up to one-half of stroke patients and has debilitating effects, contributing to diminished activities of daily living, quality of life, pain, and functional impairments. Botulinum toxin (BoNT) is proven to be safe and effective in the treatment of focal poststroke spasticity. The aim of this review is to highlight BoNT and its potential in the treatment of upper and lower limb poststroke spasticity. We review evidence for the efficacy of BoNT type A and B formulations and address considerations of optimal injection technique, patient and caregiver satisfaction, and potential adverse effects of BoNT. Dove Medical Press 2016-03-08 /pmc/articles/PMC4789850/ /pubmed/27022247 http://dx.doi.org/10.2147/DDDT.S80804 Text en © 2016 Kaku and Simpson. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Kaku, Michelle
Simpson, David M
Spotlight on botulinum toxin and its potential in the treatment of stroke-related spasticity
title Spotlight on botulinum toxin and its potential in the treatment of stroke-related spasticity
title_full Spotlight on botulinum toxin and its potential in the treatment of stroke-related spasticity
title_fullStr Spotlight on botulinum toxin and its potential in the treatment of stroke-related spasticity
title_full_unstemmed Spotlight on botulinum toxin and its potential in the treatment of stroke-related spasticity
title_short Spotlight on botulinum toxin and its potential in the treatment of stroke-related spasticity
title_sort spotlight on botulinum toxin and its potential in the treatment of stroke-related spasticity
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789850/
https://www.ncbi.nlm.nih.gov/pubmed/27022247
http://dx.doi.org/10.2147/DDDT.S80804
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