Ezh2 Controls an Early Hematopoietic Program and Growth and Survival Signaling in Early T Cell Precursor Acute Lymphoblastic Leukemia

Early T cell precursor acute lymphoblastic leukemia (ETP-ALL) is an aggressive subtype of ALL distinguished by stem-cell-associated and myeloid transcriptional programs. Inactivating alterations of Polycomb repressive complex 2 components are frequent in human ETP-ALL, but their functional role is l...

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Detalles Bibliográficos
Autores principales: Danis, Etienne, Yamauchi, Taylor, Echanique, Kristen, Zhang, Xi, Haladyna, Jessica N., Riedel, Simone S., Zhu, Nan, Xie, Huafeng, Orkin, Stuart H., Armstrong, Scott A., Bernt, Kathrin M., Neff, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790111/
https://www.ncbi.nlm.nih.gov/pubmed/26904942
http://dx.doi.org/10.1016/j.celrep.2016.01.064

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