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Levothyroxine effects on depressive symptoms and limbic glucose metabolism in bipolar disorder: a randomized, placebo-controlled positron emission tomography study
Adding supraphysiologic doses of levothyroxine (L-T4) to standard treatment for bipolar depression shows promise, but the mechanisms underlying clinical improvement are unknown. In a previous pilot study, L-T4 treatment reduced depression scores and activity within the anterior limbic network. Here...
Autores principales: | Bauer, M, Berman, S, Stamm, T, Plotkin, M, Adli, M, Pilhatsch, M, London, E D, Hellemann, G S, Whybrow, P C, Schlagenhauf, F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790155/ https://www.ncbi.nlm.nih.gov/pubmed/25600111 http://dx.doi.org/10.1038/mp.2014.186 |
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