Examining the Clinical Effectiveness of Non-Carbapenem β-Lactams for the Treatment of Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae

Treatment options for extended-spectrum β-lactamase-producing Enterobacteriaceae are limited. Piperacillin-tazobactam and cefepime represent potential alternative treatment options; however, large prospective studies are lacking. This review evaluates the current literature regarding use of piperaci...

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Detalles Bibliográficos
Autores principales: Gibble, Allison M., Gross, Alan E., Huang, Angela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790318/
https://www.ncbi.nlm.nih.gov/pubmed/27025645
http://dx.doi.org/10.3390/antibiotics4040653
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author Gibble, Allison M.
Gross, Alan E.
Huang, Angela M.
author_facet Gibble, Allison M.
Gross, Alan E.
Huang, Angela M.
author_sort Gibble, Allison M.
collection PubMed
description Treatment options for extended-spectrum β-lactamase-producing Enterobacteriaceae are limited. Piperacillin-tazobactam and cefepime represent potential alternative treatment options; however, large prospective studies are lacking. This review evaluates the current literature regarding use of piperacillin-tazobactam and cefepime for the treatment of extended-spectrum β-lactamase-producing Enterobacteriaceae. Antimicrobial stewardship programs can play a key role in guiding the best practices for the management of these challenging infections.
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spelling pubmed-47903182016-03-24 Examining the Clinical Effectiveness of Non-Carbapenem β-Lactams for the Treatment of Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae Gibble, Allison M. Gross, Alan E. Huang, Angela M. Antibiotics (Basel) Review Treatment options for extended-spectrum β-lactamase-producing Enterobacteriaceae are limited. Piperacillin-tazobactam and cefepime represent potential alternative treatment options; however, large prospective studies are lacking. This review evaluates the current literature regarding use of piperacillin-tazobactam and cefepime for the treatment of extended-spectrum β-lactamase-producing Enterobacteriaceae. Antimicrobial stewardship programs can play a key role in guiding the best practices for the management of these challenging infections. MDPI 2015-12-15 /pmc/articles/PMC4790318/ /pubmed/27025645 http://dx.doi.org/10.3390/antibiotics4040653 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Gibble, Allison M.
Gross, Alan E.
Huang, Angela M.
Examining the Clinical Effectiveness of Non-Carbapenem β-Lactams for the Treatment of Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae
title Examining the Clinical Effectiveness of Non-Carbapenem β-Lactams for the Treatment of Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae
title_full Examining the Clinical Effectiveness of Non-Carbapenem β-Lactams for the Treatment of Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae
title_fullStr Examining the Clinical Effectiveness of Non-Carbapenem β-Lactams for the Treatment of Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae
title_full_unstemmed Examining the Clinical Effectiveness of Non-Carbapenem β-Lactams for the Treatment of Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae
title_short Examining the Clinical Effectiveness of Non-Carbapenem β-Lactams for the Treatment of Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae
title_sort examining the clinical effectiveness of non-carbapenem β-lactams for the treatment of extended-spectrum β-lactamase-producing enterobacteriaceae
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790318/
https://www.ncbi.nlm.nih.gov/pubmed/27025645
http://dx.doi.org/10.3390/antibiotics4040653
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