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The Antimicrobial Stewardship Approach to Combating Clostridium Difficile
Clostridium difficile remains a major public health threat and continues to contribute to excess morbidity, mortality and healthcare costs. Antimicrobial stewardship programs have demonstrated success in combating C. difficile, primarily through antibiotic restrictive strategies. As the incidence an...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790327/ https://www.ncbi.nlm.nih.gov/pubmed/27025621 http://dx.doi.org/10.3390/antibiotics4020198 |
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author | Wenzler, Eric Mulugeta, Surafel G. Danziger, Larry H. |
author_facet | Wenzler, Eric Mulugeta, Surafel G. Danziger, Larry H. |
author_sort | Wenzler, Eric |
collection | PubMed |
description | Clostridium difficile remains a major public health threat and continues to contribute to excess morbidity, mortality and healthcare costs. Antimicrobial stewardship programs have demonstrated success in combating C. difficile, primarily through antibiotic restrictive strategies. As the incidence and prevalence of C. difficile associate disease continues to increase both in the hospital and community setting, additional stewardship approaches are needed. This manuscript reviews stewardship interventions that have been successful against C. difficile associated disease and proposes future tactics that antimicrobial stewardship programs may employ to develop a more global approach to combat this difficult pathogen. |
format | Online Article Text |
id | pubmed-4790327 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-47903272016-03-24 The Antimicrobial Stewardship Approach to Combating Clostridium Difficile Wenzler, Eric Mulugeta, Surafel G. Danziger, Larry H. Antibiotics (Basel) Review Clostridium difficile remains a major public health threat and continues to contribute to excess morbidity, mortality and healthcare costs. Antimicrobial stewardship programs have demonstrated success in combating C. difficile, primarily through antibiotic restrictive strategies. As the incidence and prevalence of C. difficile associate disease continues to increase both in the hospital and community setting, additional stewardship approaches are needed. This manuscript reviews stewardship interventions that have been successful against C. difficile associated disease and proposes future tactics that antimicrobial stewardship programs may employ to develop a more global approach to combat this difficult pathogen. MDPI 2015-06-17 /pmc/articles/PMC4790327/ /pubmed/27025621 http://dx.doi.org/10.3390/antibiotics4020198 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Wenzler, Eric Mulugeta, Surafel G. Danziger, Larry H. The Antimicrobial Stewardship Approach to Combating Clostridium Difficile |
title | The Antimicrobial Stewardship Approach to Combating Clostridium Difficile |
title_full | The Antimicrobial Stewardship Approach to Combating Clostridium Difficile |
title_fullStr | The Antimicrobial Stewardship Approach to Combating Clostridium Difficile |
title_full_unstemmed | The Antimicrobial Stewardship Approach to Combating Clostridium Difficile |
title_short | The Antimicrobial Stewardship Approach to Combating Clostridium Difficile |
title_sort | antimicrobial stewardship approach to combating clostridium difficile |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790327/ https://www.ncbi.nlm.nih.gov/pubmed/27025621 http://dx.doi.org/10.3390/antibiotics4020198 |
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