Host Defense Peptides from Asian Frogs as Potential Clinical Therapies

Host defense peptides (HDPs) are currently major focal points of medical research as infectious microbes are gaining resistance to existing drugs. They are effective against multi-drug resistant pathogens due to their unique primary target, biological membranes, and their peculiar mode of action. Ev...

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Detalles Bibliográficos
Autores principales: Kumar, Vineeth T.V., Holthausen, David, Jacob, Joshy, George, Sanil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790330/
https://www.ncbi.nlm.nih.gov/pubmed/27025618
http://dx.doi.org/10.3390/antibiotics4020136
Descripción
Sumario:Host defense peptides (HDPs) are currently major focal points of medical research as infectious microbes are gaining resistance to existing drugs. They are effective against multi-drug resistant pathogens due to their unique primary target, biological membranes, and their peculiar mode of action. Even though HDPs from 60 Asian frog species belonging to 15 genera have been characterized, research into these peptides is at a very early stage. The purpose of this review is to showcase the status of peptide research in Asia. Here we provide a summary of HDPs from Asian frogs.

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