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Rifampicin Resistance: Fitness Costs and the Significance of Compensatory Evolution
Seventy years after the introduction of antibiotic chemotherapy to treat tuberculosis, problems caused by drug-resistance in Mycobacterium tuberculosis have become greater than ever. The discovery and development of novel drugs and drug combination therapies will be critical to managing these proble...
Autores principales: | Hughes, Diarmaid, Brandis, Gerrit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790335/ https://www.ncbi.nlm.nih.gov/pubmed/27029299 http://dx.doi.org/10.3390/antibiotics2020206 |
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