The Effects of Two Novel Copper-Based Formulations on Helicobacter pylori

We investigated the effects of two novel copper-based inorganic formulations for their activity against 60 isolates of Helicobacter pylori (Hp). The two copper-based formulations were tested against three NCTC Helicobacter pylori isolates and 57 clinical strains isolated from the UK and Italy in tim...

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Autores principales: Saracino, Ilaria M., Zaccaro, Cristina, Lo Re, Giobvanna, Vaira, Dino, Holton, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790339/
https://www.ncbi.nlm.nih.gov/pubmed/27029303
http://dx.doi.org/10.3390/antibiotics2020265
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author Saracino, Ilaria M.
Zaccaro, Cristina
Lo Re, Giobvanna
Vaira, Dino
Holton, John
author_facet Saracino, Ilaria M.
Zaccaro, Cristina
Lo Re, Giobvanna
Vaira, Dino
Holton, John
author_sort Saracino, Ilaria M.
collection PubMed
description We investigated the effects of two novel copper-based inorganic formulations for their activity against 60 isolates of Helicobacter pylori (Hp). The two copper-based formulations were tested against three NCTC Helicobacter pylori isolates and 57 clinical strains isolated from the UK and Italy in time-kill assays. Both copper-based formulations were bio-cidal against all Helicobacter pylori strains tested reducing the viable count by 4–5 log within 2 h. These two copper-based anti-microbial agents deserve further study in relation to the treatment of H. pylori-related gastric disease.
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spelling pubmed-47903392016-03-24 The Effects of Two Novel Copper-Based Formulations on Helicobacter pylori Saracino, Ilaria M. Zaccaro, Cristina Lo Re, Giobvanna Vaira, Dino Holton, John Antibiotics (Basel) Article We investigated the effects of two novel copper-based inorganic formulations for their activity against 60 isolates of Helicobacter pylori (Hp). The two copper-based formulations were tested against three NCTC Helicobacter pylori isolates and 57 clinical strains isolated from the UK and Italy in time-kill assays. Both copper-based formulations were bio-cidal against all Helicobacter pylori strains tested reducing the viable count by 4–5 log within 2 h. These two copper-based anti-microbial agents deserve further study in relation to the treatment of H. pylori-related gastric disease. MDPI 2013-05-21 /pmc/articles/PMC4790339/ /pubmed/27029303 http://dx.doi.org/10.3390/antibiotics2020265 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Saracino, Ilaria M.
Zaccaro, Cristina
Lo Re, Giobvanna
Vaira, Dino
Holton, John
The Effects of Two Novel Copper-Based Formulations on Helicobacter pylori
title The Effects of Two Novel Copper-Based Formulations on Helicobacter pylori
title_full The Effects of Two Novel Copper-Based Formulations on Helicobacter pylori
title_fullStr The Effects of Two Novel Copper-Based Formulations on Helicobacter pylori
title_full_unstemmed The Effects of Two Novel Copper-Based Formulations on Helicobacter pylori
title_short The Effects of Two Novel Copper-Based Formulations on Helicobacter pylori
title_sort effects of two novel copper-based formulations on helicobacter pylori
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790339/
https://www.ncbi.nlm.nih.gov/pubmed/27029303
http://dx.doi.org/10.3390/antibiotics2020265
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