Downregulation of vascular endothelial growth factor receptor-2 under oxidative stress conditions is mediated by β-transduction repeat-containing protein via glycogen synthase kinase-3β signaling

Vascular endothelial growth factor receptor-2 (VEGFR-2), which is a key determinant of the angiogenecic response, is decreased in diabetic mice under oxidative stress. β-transduction repeat-containing protein (β-TrCP) has been reported to participate in VEGFR-2 degradation in thyroid cancer cells. A...

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Detalles Bibliográficos
Autores principales: WU, WEN, ZHANG, DAIMIN, PAN, DAORONG, ZUO, GUANGFENG, REN, XIAOMIN, CHEN, SHAOLIANG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790698/
https://www.ncbi.nlm.nih.gov/pubmed/26935904
http://dx.doi.org/10.3892/ijmm.2016.2493

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