Correlation of Utrophin Levels with the Dystrophin Protein Complex and Muscle Fibre Regeneration in Duchenne and Becker Muscular Dystrophy Muscle Biopsies

Duchenne muscular dystrophy is a severe and currently incurable progressive neuromuscular condition, caused by mutations in the DMD gene that result in the inability to produce dystrophin. Lack of dystrophin leads to loss of muscle fibres and a reduction in muscle mass and function. There is evidenc...

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Detalles Bibliográficos
Autores principales: Janghra, Narinder, Morgan, Jennifer E., Sewry, Caroline A., Wilson, Francis X., Davies, Kay E., Muntoni, Francesco, Tinsley, Jonathon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790853/
https://www.ncbi.nlm.nih.gov/pubmed/26974331
http://dx.doi.org/10.1371/journal.pone.0150818

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