Role of IGFBP7 in Diabetic Nephropathy: TGF-β1 Induces IGFBP7 via Smad2/4 in Human Renal Proximal Tubular Epithelial Cells

Tubular injury is one of the important determinants of progressive renal failure in diabetic nephropathy (DN), and TGF-β1 has been implicated in the pathogenesis of tubulointerstitial disease that characterizes proteinuric renal disease. The aim of this study was to identify novel therapeutic target...

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Detalles Bibliográficos
Autores principales: Watanabe, Jun, Takiyama, Yumi, Honjyo, Jun, Makino, Yuichi, Fujita, Yukihiro, Tateno, Masatoshi, Haneda, Masakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790858/
https://www.ncbi.nlm.nih.gov/pubmed/26974954
http://dx.doi.org/10.1371/journal.pone.0150897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790858/
https://www.ncbi.nlm.nih.gov/pubmed/26974954
http://dx.doi.org/10.1371/journal.pone.0150897

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