Cargando…

Pharmacokinetics and Bioequivalence of Two Formulations of Febuxostat 40-Mg and 80-Mg Tablets: A Randomized, Open-Label, 4-Way Crossover Study in Healthy Chinese Male Volunteers

The present study aimed to investigate the pharmacokinetic properties of febuxostat in healthy Chinese male volunteers and evaluate whether the two formulations of febuxostat 40-mg and 80-mg tablets are bioequivalent. A randomized, open-label, 4-way crossover study was conducted in healthy Chinese m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Luo, Zhu, Nan, Feng, Miao, Jia, Chen, Zhihui, Li, Mei, Liang, Maozhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790952/ https://www.ncbi.nlm.nih.gov/pubmed/26974539 http://dx.doi.org/10.1371/journal.pone.0150661

Ejemplares similares

Bioequivalence of generic alendronate sodium tablets (70 mg) to Fosamax(®) tablets (70 mg) in fasting, healthy volunteers: a randomized, open-label, three-way, reference-replicated crossover study
por: Zhang, Yifan, et al.
Publicado: (2017)

The Bioequivalence of Two Peficitinib Formulations, and the Effect of Food on the Pharmacokinetics of Peficitinib: Two‐Way Crossover Studies of a Single Dose of 150 mg Peficitinib in Healthy Volunteers
por: Shibata, Mai, et al.
Publicado: (2020)

Bioequivalence and Pharmacokinetic Evaluation of Two Formulations of Risperidone 2 mg: An Open-Label, Single-Dose, Fasting, Randomized-Sequence, Two-Way Crossover Study in Healthy Male Chinese Volunteers
por: Liu, Yun, et al.
Publicado: (2012)

Bioequivalence of the 4-mg Oral Granules and Chewable Tablet Formulations of Montelukast
por: Knorr, Barbara, et al.
Publicado: (2010)

Bioequivalence Study of 100-mg Cilostazol Tablets in Healthy Thai Adult Volunteers
por: Chatsiricharoenkul, Somruedee, et al.
Publicado: (2019)

Pharmacokinetics and Bioequivalence of Two Formulations of Valsartan 80 mg Capsules: A Randomized, Single Dose, 4-Period Crossover Study in Healthy Chinese Volunteers Under Fasting and Fed Conditions
por: Wu, Qingqing, et al.
Publicado: (2020)

Bioequivalence Study of Two Formulations of Ibandronic Acid 150-mg Film-Coated Tablets in Healthy Volunteers Under Fasting Conditions: A Randomized, Open-Label, Three-Way, Reference-Replicated Crossover Study
por: Filipe, Augusto, et al.
Publicado: (2014)

Bioequivalence Comparison of Two Formulations of Fixed-Dose Combination Glimepiride/Metformin (2/500 mg)Tablets in Healthy Volunteers
por: Jung, Sang-hoon, et al.
Publicado: (2014)

Pharmacokinetics and bioequivalence assessment of optimized directly compressible Aceclofenac (100 mg) tablet formulation in healthy human subjects
por: Bushra, Rabia, et al.
Publicado: (2020)

Bioequivalence Study of Two Orodispersible Rizatriptan Formulations of 10 mg in Healthy Volunteers
por: Cánovas, Mercè, et al.
Publicado: (2016)

Single-Dose, Randomized, Open-Label, Two-Way, Crossover Bioequivalence Study of Two Formulations of Pregabalin 300 mg Hard Capsules in Healthy Volunteers Under Fasting Conditions
por: Filipe, Augusto, et al.
Publicado: (2015)

Bioavailability of everolimus administered as a single 5 mg tablet versus five 1 mg tablets: a randomized, open-label, two-way crossover study of healthy volunteers
por: Thudium, Karen, et al.
Publicado: (2015)

Three-way, three-period, crossover bioequivalence study of single oral dose of three brands of 300 mg phenytoin sodium tablets marketed in India, on healthy Indian human volunteers
por: Doshi, Maulik S., et al.
Publicado: (2013)

Pharmacokinetic comparison of two bazedoxifene acetate 20 mg tablet formulations in healthy Korean male volunteers
por: Yeun, Ji-Sun, et al.
Publicado: (2020)

Evaluation of Bioequivalency and Pharmacokinetic Parameters for Two Formulations of Glimepiride 1-mg in Chinese Subjects
por: Ju, Gehang, et al.
Publicado: (2020)

A Single‐blind, Randomized, Single‐dose, Two‐sequence, Two‐period, Crossover Study to Assess the Bioequivalence between Two Oral Tablet Formulations of Rivaroxaban 20 mg in Healthy Mexican Volunteers
por: Genis‐Najera, Luis, et al.
Publicado: (2022)

Bioequivalence study of a new sildenafil 100 mg orodispersible film compared to the conventional film-coated 100 mg tablet administered to healthy male volunteers
por: Radicioni, Milko, et al.
Publicado: (2017)

A Randomized, Crossover, Single-Dose Bioequivalence Study of Two Extended-Release Tablets of Donepezil 23 mg in Healthy Human Volunteers under Fasting and Fed States
por: Gadiko, Chaitanya, et al.
Publicado: (2013)

Bioequivalence of 2 Naproxen Sodium Tablet Formulations in Healthy Male and Female Volunteers
por: Sugár, Dalma, et al.
Publicado: (2019)

Comparative bioequivalence studies of tramadol hydrochloride sustained-release 200 mg tablets
por: Khandave, Suhas S, et al.
Publicado: (2010)

Inhibitory effects of intravenous lansoprazole 30 mg and pantoprazole 40 mg twice daily on intragastric acidity in healthy Chinese volunteers: A randomized, open-labeled, two-way crossover study
por: Zhan, Xian-Bao, et al.
Publicado: (2012)

Relative Bioavailability and Bioequivalence of Brivaracetam 10 mg/mL Oral Solution and 50‐mg Film‐Coated Tablet
por: Otoul, Christian, et al.
Publicado: (2016)

Safety and pharmacokinetic comparison between fenofibric acid 135 mg capsule and 110 mg enteric-coated tablet in healthy volunteers
por: Seo, Yu-Bin, et al.
Publicado: (2023)

Bioequivalence Study Of A Fixed-Dose Combination Tablet Containing Melitracen 10 mg And Flupentixol 0.5 mg In Healthy Chinese Volunteers Under Fasted And Fed Conditions
por: Wu, Lihua, et al.
Publicado: (2019)

Levocetirizine Oral Disintegrating Tablet: A Randomized Open‐Label Crossover Bioequivalence Study in Healthy Japanese Volunteers
por: Ino, Hiroko, et al.
Publicado: (2020)

The Bioequivalence of Tafamidis 61‐mg Free Acid Capsules and Tafamidis Meglumine 4 × 20‐mg Capsules in Healthy Volunteers
por: Lockwood, Peter A., et al.
Publicado: (2020)

Pharmacokinetic Bioequivalence of Two Inhaled Tiotropium Bromide Formulations in Healthy Volunteers
por: Algorta, Jaime, et al.
Publicado: (2016)

A Comparative Pharmacokinetic Study of Fexuprazan 10 mg: Demonstrating Bioequivalence with the Reference Formulation and Evaluating Steady State
por: Shin, Wonsuk, et al.
Publicado: (2023)

Comparative Bioequivalence of Tablet and Capsule Formulations of Ulotaront and the Effect of Food on the Pharmacokinetics of the Tablet Form in Humans
por: Chen, Yu-Luan, et al.
Publicado: (2023)

Pharmacokinetics and Bioequivalence of Fudosteine in Healthy Chinese Volunteers Under Fasting and Fed Conditions: A 4‐Way Replicate Crossover Study
por: Zhu, Mingxue, et al.
Publicado: (2022)

Pharmacokinetics and Bioequivalence Evaluation of Cyclobenzaprine Tablets
por: Brioschi, Tatiane Maria de Lima Souza, et al.
Publicado: (2013)

Pharmacokinetic properties and bioequivalence of gefitinib 250 mg in healthy Korean male subjects
por: Moon, Seol Ju, et al.
Publicado: (2021)

Pharmacokinetics and Bioequivalence of Abiraterone Acetate Tablets in Healthy Chinese Volunteers: An Open, Randomized, Single-Dose, Three-Period, Three-Sequence Crossover Study
por: Wu, Zhao-xin, et al.
Publicado: (2023)

Pilot study: bioequivalence of dihydroartemisinin in dihydroartemisinin-piperaquine tablet generic formulation in healthy Indonesian volunteers
por: Isnawati, Ani, et al.
Publicado: (2023)

Safety and pharmacokinetic profile of fixed-dose ivermectin with an innovative 18mg tablet in healthy adult volunteers
por: Muñoz, Jose, et al.
Publicado: (2018)

Pharmacokinetics and bioequivalence study of esomeprazole magnesium enteric-coated tablets 20 mg in healthy Chinese subjects under fasting and fed conditions
por: Ding, Ying, et al.
Publicado: (2023)

Pharmacokinetics and Bioequivalence of Memantine Tablet and a New Dry Syrup Formulation in Healthy Japanese Males: Two Single-Dose Crossover Studies
por: Maekawa, Yutaro, et al.
Publicado: (2019)

Bioequivalence of two tacrolimus 1-mg formulations under fasting conditions in healthy subjects: A randomized, two-period crossover trial
por: Mohanty, Lalitendu, et al.
Publicado: (2020)

Pharmacokinetics and Bioequivalence Study of Hydroxychloroquine Sulfate Tablets in Chinese Healthy Volunteers by LC–MS/MS
por: Fan, Hong-wei, et al.
Publicado: (2015)

Pharmacokinetic Effects of Simultaneous Administration of Single-Dose Gabapentin 500 mg and Zolpidem Tartrate 10 mg in Healthy Volunteers: A Randomized, Open-Label, Crossover Trial
por: Galitz, Lawrence A., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_hc1nf50be654j2tncfi5pnplva