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Regulatory roles of conserved phosphorylation sites in the activation T-loop of the MAP kinase ERK1
The catalytic domains of most eukaryotic protein kinases are highly conserved in their primary structures. Their phosphorylation within the well-known activation T-loop, a variable region between protein kinase catalytic subdomains VII and VIII, is a common mechanism for stimulation of their phospho...
Autores principales: | Lai, Shenshen, Pelech, Steven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791125/ https://www.ncbi.nlm.nih.gov/pubmed/26823016 http://dx.doi.org/10.1091/mbc.E15-07-0527 |
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