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Ceramide limits phosphatidylinositol-3-kinase C2β-controlled cell motility in ovarian cancer: potential of ceramide as a metastasis-suppressor lipid

Targeting cell motility, which is required for dissemination and metastasis, has therapeutic potential for ovarian cancer metastasis, and regulatory mechanisms of cell motility need to be uncovered for developing novel therapeutics. Invasive ovarian cancer cells spontaneously formed protrusions, suc...

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Detalles Bibliográficos
Autores principales: Kitatani, Kazuyuki, Toshinori, Usui, Sriraman, Shravan Kumar, Toyoshima, Masafumi, Ishibashi, Masumi, Shigeta, Shogo, Nagase, Satoru, Sakamoto, Masahiro, Ogiso, Hideo, Okazaki, Toshiro, Hannun, Yusuf A., Torchilin, Vladimir P., Yaegashi, Nobuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791218/
https://www.ncbi.nlm.nih.gov/pubmed/26364609
http://dx.doi.org/10.1038/onc.2015.330