The NKG2D – IL-15 signaling pathway contributes to T-cell mediated pathology in inflammatory myopathies

NKG2D is an activating receptor on T cells, which has been implicated in the pathogenesis of autoimmune diseases. T cells are critically involved in idiopathic inflammatory myopathies (IIM) and have been proposed as specific therapeutic targets. However, the mechanisms underlying T cell-mediated pro...

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Detalles Bibliográficos
Autores principales: Ruck, Tobias, Bittner, Stefan, Afzali, Ali Maisam, Göbel, Kerstin, Glumm, Sarah, Kraft, Peter, Sommer, Claudia, Kleinschnitz, Christoph, Preuβe, Corinna, Stenzel, Werner, Wiendl, Heinz, Meuth, Sven G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791228/
https://www.ncbi.nlm.nih.gov/pubmed/26646698

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