Proteasome inhibition mediates p53 reactivation and anti-cancer activity of 6-Gingerol in cervical cancer cells

Human papilloma virus (HPV) expressing E6 and E7 oncoproteins, is known to inactivate the tumor suppressor p53 through proteasomal degradation in cervical cancers. Therefore, use of small molecules for inhibition of proteasome function and induction of p53 reactivation is a promising strategy for in...

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Detalles Bibliográficos
Autores principales: Rastogi, Namrata, Duggal, Shivali, Singh, Shailendra Kumar, Porwal, Konica, Srivastava, Vikas Kumar, Maurya, Rakesh, Bhatt, Madan L.B., Mishra, Durga Prasad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper: Chromosome
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791234/
https://www.ncbi.nlm.nih.gov/pubmed/26621832

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