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Mismatch repair gene defects in sporadic colorectal cancer enhance immune surveillance
BACKGROUND: There is evidence that colorectal cancers (CRC) with DNA mismatch repair deficiency (MMR-D) are associated with a better prognosis than the generality of large bowel malignancies. Since an active immune surveillance process has been demonstrated to influence CRC outcome, we investigated...
Autores principales: | Scarpa, Marco, Ruffolo, Cesare, Canal, Fabio, Scarpa, Melania, Basato, Silvia, Erroi, Francesca, Fiorot, Alain, Dall'Agnese, Lucia, Pozza, Anna, Porzionato, Andrea, Castagliuolo, Ignazio, Dei Tos, Angelo P., Bassi, Nicolò, Castoro, Carlo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791244/ https://www.ncbi.nlm.nih.gov/pubmed/26496037 |
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