Cargando…

Genomic dynamics associated with malignant transformation in IDH1 mutated gliomas

The genomic mechanism responsible for malignant transformation remains an open question for glioma researchers, where differing conclusions have been drawn based on diverse study conditions. Therefore, it is essential to secure direct evidence using longitudinal samples from the same patient. Moreov...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Chul-Kee, Park, Inho, Lee, Seungmook, Sun, Choong-Hyun, Koh, Youngil, Park, Sung-Hye, Kim, Ja Eun, Yun, Hongseok, Lee, Se-Hoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791257/ https://www.ncbi.nlm.nih.gov/pubmed/26524630

Ejemplares similares

Detection of a Distinctive Genomic Signature in Rhabdoid Glioblastoma, A Rare Disease Entity Identified by Whole Exome Sequencing and Whole Transcriptome Sequencing()()()
por: Koh, Youngil, et al.
Publicado: (2015)

Genomic profiles of IDH-mutant gliomas: MYCN-amplified IDH-mutant astrocytoma had the worst prognosis
por: Lee, Kwanghoon, et al.
Publicado: (2023)

NPM1 as a potential therapeutic target for atypical teratoid/rhabdoid tumors
por: Phi, Ji Hoon, et al.
Publicado: (2019)

A scientific treatment approach for acute mast cell leukemia: using a strategy based on next-generation sequencing data
por: Youk, Jeonghwan, et al.
Publicado: (2016)

Prognosis of Glioblastoma With Oligodendroglioma Component is Associated With the IDH1 Mutation and MGMT Methylation Status()
por: Myung, Jae Kyung, et al.
Publicado: (2014)

Epigenetic Reprogramming for Targeting IDH-Mutant Malignant Gliomas
por: Park, Jong-Whi, et al.
Publicado: (2019)

Mechanism for enhanced 5-aminolevulinic acid fluorescence in isocitrate dehydrogenase 1 mutant malignant gliomas
por: Kim, Ja Eun, et al.
Publicado: (2015)

Metabolic Profiling of IDH Mutation and Malignant Progression in Infiltrating Glioma
por: Jalbert, Llewellyn E., et al.
Publicado: (2017)

Radiotherapy delays malignant transformation and prolongs survival in patients with IDH-mutant gliomas
por: Liu, Yanwei, et al.
Publicado: (2022)

IDH1/2 mutations in acute myeloid leukemia
por: Byun, Ja Min, et al.
Publicado: (2022)

The frequency and prognostic effect of TERT promoter mutation in diffuse gliomas
por: Lee, Yujin, et al.
Publicado: (2017)

Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas
por: Killela, Patrick J., et al.
Publicado: (2014)

Mutation Analysis of IDH1 in Paired Gliomas Revealed IDH1 Mutation Was Not Associated with Malignant Progression but Predicted Longer Survival
por: Yao, Yu, et al.
Publicado: (2013)

Survival and Malignant Transformation of Pineal Parenchymal Tumors: A 30-Year Retrospective Analysis in a Single-Institution
por: Park, Tae-Hwan, et al.
Publicado: (2023)

Mathematical Modeling and Mutational Analysis Reveal Optimal Therapy to Prevent Malignant Transformation in Grade II IDH-Mutant Gliomas
por: Aoki, Kosuke, et al.
Publicado: (2021)

MYB/MYBL1::QKI fusion-positive diffuse glioma
por: Suh, Ye Yoon, et al.
Publicado: (2023)

Toxicity Profile of Temozolomide in the Treatment of 300 Malignant Glioma Patients in Korea
por: Bae, So Hyun, et al.
Publicado: (2014)

Consequences of IDH1/2 Mutations in Gliomas and an Assessment of Inhibitors Targeting Mutated IDH Proteins
por: Kaminska, Bozena, et al.
Publicado: (2019)

Malignant Progression of an IDH Mutant Brainstem Glioma in Adult
por: SANO, Kenshi, et al.
Publicado: (2021)

Clinical and Genomic Characteristics of Adult Diffuse Midline Glioma
por: Park, Changhee, et al.
Publicado: (2021)

A single-institution retrospective analysis of pathologically determined malignant transformation in IDH mutant glioma patients
por: Liu, Vicki, et al.
Publicado: (2023)

Immunohistochemical Analysis of ATRX, IDH1 and p53 in Glioblastoma and Their Correlations with Patient Survival
por: Chaurasia, Ajay, et al.
Publicado: (2016)

Integrated genomic analyses identify frequent gene fusion events and VHL inactivation in gastrointestinal stromal tumors
por: Kang, Guhyun, et al.
Publicado: (2015)

Implications of Concurrent IDH1 and IDH2 Mutations on Survival in Glioma—A Case Report and Systematic Review
por: Yuile, Alexander, et al.
Publicado: (2022)

The comparison of clinical and biological characteristics between IDH1 and IDH2 mutations in gliomas
por: Wang, Hao-Yuan, et al.
Publicado: (2016)

Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas
por: Jiao, Yuchen, et al.
Publicado: (2012)

IDH1 Mutation in Gliomas in Mosul City - Iraq
por: Saeed, Mohammed Sami
Publicado: (2015)

Pharmacoresistant seizures and IDH mutation in low-grade gliomas
por: Correia, Carlos Eduardo, et al.
Publicado: (2021)

Seizures in patients with IDH-mutated lower grade gliomas
por: Carstam, Louise, et al.
Publicado: (2022)

Swin Transformer Improves the IDH Mutation Status Prediction of Gliomas Free of MRI-Based Tumor Segmentation
por: Wu, Jiangfen, et al.
Publicado: (2022)

Isocitrate Dehydrogenase IDH1 and IDH2 Mutations in Human Cancer: Prognostic Implications for Gliomas
por: Murugan, A. K., et al.
Publicado: (2022)

Interrogation of IDH1 Status in Gliomas by Fourier Transform Infrared Spectroscopy
por: Cameron, James M., et al.
Publicado: (2020)

Leukemic stem cell phenotype is associated with mutational profile in acute myeloid leukemia
por: Han, Heejoo, et al.
Publicado: (2021)

Estimation of the occurrence rates of IDH1 and IDH2 mutations in gliomas and the reconsideration of IDH-wildtype anaplastic astrocytomas: an institutional experience
por: Cho, Uiju, et al.
Publicado: (2021)

IDH mutations but not TERTp mutations are associated with seizures in lower-grade gliomas
por: Duan, Wen-chao, et al.
Publicado: (2018)

Expression level of hTERT is regulated by somatic mutation and common single nucleotide polymorphism at promoter region in glioblastoma
por: Park, Chul-Kee, et al.
Publicado: (2014)

IDH1 mutation analysis – an example of putative glioma marker
por: Lewandowska, Marzena, et al.
Publicado: (2012)

IDH1 mutation detection by droplet digital PCR in glioma
por: Wang, Jing, et al.
Publicado: (2015)

IDH mutation-specific radiomic signature in lower-grade gliomas
por: Liu, Xing, et al.
Publicado: (2019)

MPC-05 TUMOR RELATED EPILEPSY AND IDH MUTATIONS IN GLIOMAS
por: Wakabayashi, Hikaru, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_h8803fmf6r99hf6uflutk0263h