Enhanced therapeutic effect of Adriamycin on multidrug resistant breast cancer by the ABCG2-siRNA loaded polymeric nanoparticles assisted with ultrasound

The overexpression of the breast cancer resistance protein (ABCG2) confers resistance to Adriamycin (ADR) in breast cancer. The silencing of ABCG2 using small interfering RNA (siRNA) could be a promising approach to overcome multidrug resistance (MDR) in cancer cells. To deliver ABCG2-siRNA effectiv...

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Detalles Bibliográficos
Autores principales: Bai, Min, Shen, Ming, Teng, Yanwei, Sun, Ying, Li, Fan, Zhang, Xiangyu, Xu, Yuanyuan, Duan, Yourong, Du, Lianfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791266/
https://www.ncbi.nlm.nih.gov/pubmed/26575421

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